Même dans les professions médicales, il est actuellement reconnu que le fructose peut avoir des effets souvent désastreux sur la fonction hépatique. C’est ce qu’ont récemment démontré les chercheurs du Centre Médical Wake Baptist Forêt en Caroline du Nord. Ils ont démontré que la consommation de ce sucre peut provoquer une stéatose hépatique non-alcoolique. Cette maladie provoque un engraissement du foie, comme pour le foie gras chez l’oie. Mais il faut savoir que dans certains cas, cette dysfonction hépatique peut déboucher sur des cirrhoses.

The "American Journal of Clinical Nutrition" (AJCN) recently published a study that found that fructose consumption can quickly trigger significant liver damage, while all other liver parameters appear to remain "normal" and there are no other pathological manifestations.

Ce trouble peut parfois se manifester par une prise de poids qui peut quelquefois mener à l’obésité. Chez quelques autres consommateurs de fructose, on verra apparaître un diabète.

You may think that fructose will give you fewer calories? Or that all calorie intakes are equivalent?

It's not," says Kylie Kavanagh, a professor at Wake Baptist Forest Medical Center and lead author of the study. What surprised us most was how quickly the liver was affected by the sugar and how much damage was done, even though there was no weight gain.

The research was conducted over a period of seven years as follows: a group of monkeys was provided with an all-you-can-eat buffet of low-fat food and a supplement of fructose. While the control group received a low-fat, low-fructose diet. The other factors, quantity and access to food, were absolutely equal.

In the evaluation, the researchers observed that the monkeys in the fructose supplemented group had about 50% more weight than the control group. They also had rates of diabetes 3 times higher than the control group as well as severe fatty liver disease. All of these disturbances were clearly related to fructose consumption.

Weight and liver problems are not the only health problems caused by fructose consumption

To investigate the harmful impact of this sugar, researchers took 10 monkeys of average age and weight who had never consumed fructose. The monkeys were divided into two comparable groups based on their body shapes and waist circumference.

For 6 weeks, one group was fed a calorie controlled diet containing 24% fructose. The other group received a diet with calories controlled, but containing a negligible amount of fructose. The amounts of fat, carbohydrate and protein received by both groups were identical and from different sources. All parameters and intakes were calculated so that all monkeys remained at similar weights.

After 6 weeks, the researchers took blood samples to study specific liver biomarkers. They also evaluated the bacterial composition of the monkeys' intestines.

Result, they not only found that fructose directly harmed the monkeys' livers, but also altered the gut bacterial composition. In detailing this study, the researchers realized that fructose caused intestinal permeability and an imbalance in microflora. They found up to 30% greater penetration of certain elements into the blood of monkeys that consumed fructose. According to them, these elements could damage the liver.

These sugars therefore cause leaky gut and liver damage without any other clinical manifestations such as weight gain for example.

This is a game-changer, because until now, doctors and scientists were convinced that health problems, especially those affecting the liver, were directly related to the amount of adipose tissue and to excess weight.

The latest results of these studies point in a completely different direction.

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