Did you know that exercise has a significant impact on the body's biochemistry?

Ubiquinol is the reduced form of Coenzyme Q10. Its use in this form has a significant advantage: its bioavailability. The latter is more important than CoQ10. The organism can thus use it directly without passing by the stage of reduction which is done by an enzymatic process. Ubiquinol is particularly suited to situations where this process may be more difficult to achieve. This can be the case during aging or after intensive physical exercise.

A study carried out on about twenty athletes separated into two groups evaluated the effect of ubiquinol supplementation after a period of intense exercise. For one month, they took 200 mg of ubiquinol or a placebo each day and then did 40 minutes of intense exercise. Parameters were measured before and after each exercise session.

The results showed that extreme physical activity caused a rapid drop in plasma CoQ10 concentrations, suggesting an increase in the body's needs. This also leads to a decrease in paraoxonase activity.

Thus, it was ubiquinol supplementation that prevented exercise-induced CoQ10 deprivation. These data then highlight a very rapid dynamic of CoQ10 depletion after intense exercise, following an increased demand from the body.

It should be noted, however, that this study did not improve physical performance indices or muscle damage.

Source: Orlando P et al, Effect of ubiquinol supplementation on biochemical and oxidative stress indexes after intense exercise in young athletes. Redox Report 2018, 23(1): 136-145.